Table 1 RDR Checklist

1 . Technology choices

4 . System design

• Web-based or desktop application

• Customisable for

• Relational Database or unstructured data

  ○ a specific disease(s)

• Programming Language

  ○ patient registry

• Cloud deployment vs Physical ICT infrastructure

  ○ clinical registry

• Open source vs Proprietary

• Modular design

  ○ new features

  ○ new data elemets

  ○ new ontologies

2 . Professional Software Development

5 . Security

• Appropriate software project management

• De-identification process

• Team-based software development

• Two factor authentication

• Well-structured, commented code

• Multi-level user access

• Version control

• Work groups

• Issue tracking

• Encryption

• Documentation

6. Sustainability

• Software deployment instructions

• Ease of exchange

• Functional and Unit Testing

• Effort required

• Team-based development

• Future proofing

3. Interoperable

7. Open source

• Export/import functionality

• Appropriate levels of documentation

• Webservice API

• Strategies to capture community feedback

• Data standards

• Open and transparent installation processes

• Ontology

• Deployment process detailed

  ○ Data elements

  ○ Disease elements