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Fig. 6 | Source Code for Biology and Medicine

Fig. 6

From: Simulating pedigrees ascertained for multiple disease-affected relatives

Fig. 6

Genetic Contribution Estimate. Scatter plots of the probability that a randomly selected pedigree from a sample of ascertained pedigrees is segregating a genetic variant with relative-risk of disease κ against the relative-risk of disease κ. Here we consider the effect of restricting attention to the ascertained pedigrees with nA or more disease-affected relatives. In the leftmost panel, we consider all one thousand pedigrees ascertained with two or more disease-affected relatives; in the middle panel, we consider the subset with three or more disease-affected relatives, and in the right most panel the subset with four or more disease-affected relatives

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