Fig. 8
From: PureCN: copy number calling and SNV classification using targeted short read sequencing
Comparison with existing proprietary ABSOLUTE implementation. In panel (a) and (b), our purity and ploidy estimates (y-axis), respectively, are plotted against the estimates from Foundation Medicine. Triangles indicate solutions flagged by PureCN for manual curation. c Compares copy number ratios of amplifications and homozygous deletions in 40 different samples. d shows the corresponding absolute copy numbers adjusted for purity and ploidy. Copy numbers were capped at 7 in both algorithms, the default copy number cutoffs for non-focal amplifications