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Fig. 5 | Source Code for Biology and Medicine

Fig. 5

From: PureCN: copy number calling and SNV classification using targeted short read sequencing

Fig. 5

Accuracy of germline vs. somatic variant labeling. This figure displays the allelic fractions of correctly and incorrectly labeled variants for two samples run in MuTect and PureCN without matched normal sample. The ground truth was obtained by running MuTect with matched normal sample. The first was a primary tumor sample with purity of 0.5, the second a metastasis sample with purity of 0.7. Due to the lower purity of the primary tumor sample, the distributions of allelic fraction overlap less, making the prediction easier. The bars for the 4 different categories are stacked

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