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Table 1 Networks identified in a Wormpath analysis of 1349 genes regulated upon UV radiation

From: Wormpath: searching for molecular interaction networks in Caenorhabditis elegans

  Genes involved Nodes Edges Score p-value (score) p-value (list)
1 daf-3, peb-1, myo-2, daf-36, daf-16, daf-2 6 6 23.33 0.0006 <0.0001
2 cav-1, sur-5, sma-6, lin-28, let-653, kin-15, unc-52, let-60, unc-6, ces-1, col-48, glp-1, daf-2, daf-12, F40F4.6, sqt-1, daf-16, kin-9 18 19 8.58 0.001 <0.0001
3 sbds-1, daf-3, ins-7, F26A1.9, acs-20, nhr-49, lys-7, daf-16, C26B9.3, mtl-1, agmo-1, acs-2, npp-9, myo-2, C29F9.2, daf-2, gei-7, C14A4.9, cyp-42A1, let-653, daf-36, nstp-3, T22B11.2 23 26 6.58 0.0018 <0.0001
4 cyp-42A1, daf-16, ugt-62, nhr-49, gei-7, daf-36, npp-9, lys-7, C14A4.9, C26B9.3, daf-2, F40F4.6, sbds-1, egl-15, let-756, acs-2, acs-20, ins-7, nstp-3, mtl-1, C29F9.2, agmo-1, T22B11.2, T24C12.4, daf-3, F26A1.9, ZK418.7, let-653 28 31 5.68 0.0018 <0.0001
5 cav-1, lon-3, sqt-1, unc-52, unc-6, glp-1, kin-15, F40F4.6, sqt-3, let-60, rol-6 11 12 5.58 0.009 <0.0001
6 F26A1.9, acs-2, daf-2, C29F9.2, lys-7, daf-36, agmo-1, nhr-49, sur-5, daf-3, let-653, vab-1, C14A4.9, unc-6, daf-16, ces-1, daf-12, cyp-42A1, mtl-1, C26B9.3, nstp-3, cav-1, let-60, T22B11.2, npp-9, nhr-8, kin-9, sbds-1, ins-7, acs-20, gei-7, qua-1 32 36 5.17 0.0042 <0.0001
7 unc-2, nhr-49, C14A4.9, let-653, daf-16, C29F9.2, unc-25, mrp-1, agmo-1, let-60, sbds-1, daf-2, fasn-1, daf-11, nsy-4, cyp-42A1, cav-1, lin-28, daf-12, daf-7, ins-7, mtl-1, C26B9.3, myo-2, F26A1.9, daf-3, acs-20, sir-2.1, lys-7, T22B11.2, abu-11, nstp-3, acs-2, daf-36, daf-1, gei-7, npp-9 37 42 4.81 0.003 <0.0001
8 lin-14, daf-16, daf-12, cav-1, col-17, ins-33, lin-46, lin-28 8 9 2.67 0.0814 <0.0001
9 lim-6, daf-16, unc-25, zig-2, fasn-1, daf-7 6 5 1.80 0.3028 <0.0001
10 daf-1, daf-11, mrp-1, fasn-1, unc-25, daf-16, daf-7 7 7 1.71 0.3576 <0.0001
11 sur-5, let-60, ces-1, F56D2.3, kin-9, crb-1, cav-1, let-653, phg-1, atl-1, clk-2, unc-6 12 11 1.64 0.361 <0.0001
12 ces-1, unc-6, let-60, ced-11, ced-3, kin-9, sur-5, let-653, cav-1 9 8 1.62 0.418 <0.0001
13 glp-1, cav-1, kin-15, F40F4.6, sqt-1 5 4 1.50 0.4766 <0.0001
14 peb-1, lin-31, sur-5, lin-45, kin-9, let-60, ces-1, unc-6, let-653, cav-1 10 9 1.44 0.5824 <0.0001
15 sur-5, egl-30, sqt-1, cav-1, unc-6, glp-1, ces-1, unc-52, gtl-1, mig-17, kin-9, let-653, egl-8, let-60, lev-11 15 15 1.40 0.6734 <0.0001
16 F40F4.6, ugt-62, glp-1, T24C12.4, let-756, npp-9, sqt-1, kin-15, cav-1 9 8 1.25 0.76 <0.0001
17 let-23, che-14, lin-45, sur-5, lin-26, dsl-5, peb-1, ZK418.7, lin-31 9 8 1.00 >0.9999 0.0018
18 let-23, lin-31, dsl-5, ZK418.7, col-48, bar-1 6 5 1.00 >0.9999 <0.0001
19 egl-15, dsl-5, ZK418.7, npp-9, lin-31, let-23 6 5 1.00 >0.9999 <0.0001
20 acn-1, mlt-9, nhr-23, qua-1, nhr-25 5 4 1.00 >0.9999 0.0005
21 ptr-16, ptr-1, ptr-6, ptr-10 4 4 1.00 >0.9999 <0.0001
22 sma-6, cav-1, bar-1, dsl-5, col-48 5 4 1.00 >0.9999 <0.0001
23 dpy-13, bli-4, dpy-5, dpy-6 4 3 1.00 >0.9999 <0.0001
24 nsy-4, daf-16, unc-2 3 2 1.00 >0.9999 0.0037
25 sym-5, sym-1 2 1 1.00 >0.9999 0.0046