MALINA: a web service for visual analytics of human gut microbiota whole-genome metagenomic reads

Table 1 Comparison of MALINA and existing software allowing analysis of human gut metagenomic reads

Name of software	Type	Number of included shotgun human gut microbiome samples	Supported input sequence formats				Statistical analysis					Visualization
			454	Illumina	Sanger	SOLiD	Taxonomic profiling	Functional profiling	Taxa co-occurence analysis	Sample clustering	Group comparison	Abundance plots	PCA	BCA	MDS	Hierarchical clustering
CAMERA	web-service	36	+	+	+	-	+	+	-	-	-	+	-	-	-	-
IMG/M	web-service	149	+	+	+	-	+	+	-	+	-	+	-	-	-	+
MG-RAST	web-service	13	+	+	+	-	+	+	-	+	+	+	+	-	-	+
MALINA	web-service	357	+	+	+	+	+	+	+	+	+	+	+	+	+	+
METAGENassist	web-service	39	-	-	-	-	-	-	+	+	+	+	+	-	+	+
QIIME	stand-alone	0	+	+	+	-	+	-	-	+	+	+	+	-	+	+
SmashCommunity	stand-alone	0	+	-	+	-	+	+	-	+	-	+	-	-	-	+

Note: although METAGENassist does not accept read sequences as input, it does accept precomputed feature matrices that can be obtained from reads of any of the mentioned sequencing technologies with the help of third-party software.

ISSN: 1751-0473