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Table 1 Comparison of MALINA and existing software allowing analysis of human gut metagenomic reads

From: MALINA: a web service for visual analytics of human gut microbiota whole-genome metagenomic reads

Name of software Type Number of included shotgun human gut microbiome samples Supported input sequence formats Statistical analysis Visualization
    454 Illumina Sanger SOLiD Taxonomic profiling Functional profiling Taxa co-occurence analysis Sample clustering Group comparison Abundance plots PCA BCA MDS Hierarchical clustering
CAMERA web-service 36 + + + - + + - - - + - - - -
IMG/M web-service 149 + + + - + + - + - + - - - +
MG-RAST web-service 13 + + + - + + - + + + + - - +
MALINA web-service 357 + + + + + + + + + + + + + +
METAGENassist web-service 39 - - - - - - + + + + + - + +
QIIME stand-alone 0 + + + - + - - + + + + - + +
SmashCommunity stand-alone 0 + - + - + + - + - + - - - +
  1. Note: although METAGENassist does not accept read sequences as input, it does accept precomputed feature matrices that can be obtained from reads of any of the mentioned sequencing technologies with the help of third-party software.