ParaHaplo: A program package for haplotype-based whole-genome association study using parallel computing

Table 1 List of haplotype blocks whose haplotype frequencies are significantly different (P < 0.01) between CHB and JPT.

Chromosome	Position	Haplotype block	Number of SNPs	High-Score SNP	Score		Global P-value	Gene Name	Biological Function
2	24871212	24869289-24909832	26	rs41523444	33.0		0.00774	CENPO	intron
2	205189112	205070386-205212654	69	rs12621708	33.2		0.00906	PARD3B	intron
5	18748116	18740543-18750444	5	rs11959018	32.1		0.00277
7	134114362	134099273-134115148	10	rs3807337	29.5		0.007	CALD1	intron
8	81952476	81912934-81997651	35	rs10957985	33.9	*	0.0083
9	103425694	103425657-103427263	5	rs10115450	43.5	*	0.00001	GRIN3A	intron
11	61080499	61049633-61102485	18	rs4939526	32.1		0.00421	SYT7	intron
11	115945221	115943365-115950641	8	rs4938285	31.3		0.00819
12	87163821	87149707-87191176	12	rs11104775	30.4		0.00762
13	72589237	72589149-72599947	3	rs1333099	32.1		0.00186
15	59355415	59306354-59363106	22	rs7175875	32.7		0.00294
18	74579176	74562645-74583266	10	rs5022079	30.0		0.00648
22	35929011	35927436-35929568	3	rs229562	28.0		0.00711

*Significantly different (P < 0.01) between JPT and CHB when SNP-based GWAS was used.

ISSN: 1751-0473