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Figure 1 | Source Code for Biology and Medicine

Figure 1

From: OCPAT: an online codon-preserved alignment tool for evolutionary genomic analysis of protein coding sequences

Figure 1

Workflow of OCPAT. The pipeline implements the steps as shown in the figure. The human RefSeq mRNA serves as the initial query by default. Putative orthologs are defined by sequence similarity and gene symbol. Frameshift causing substitutions are masked, and OCPAT does not distinguish true frameshifts from sequencing errors. Unlike other alignment tools, a RefSeq golden peptide sequence record guides OCPAT alignments rather than the predicted amino acid sequence derived from the mRNA record.

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Source Code for Biology and Medicine

ISSN: 1751-0473