Table 1 Enrichment of pathways associated with AD
From: PathNet: a tool for pathway analysis using topological information
Pathway (KEGG ID) | PathNet | SPIA | GSEA | Hypergeometric test | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Inc | Mod | Sev | HIP | Inc | Mod | Sev | HIP | Inc | Mod | Sev | HIP | Inc | Mod | Sev | HIP | ||
AD pathway | (5010) | 1.00 | *0.01 | *0.00 | *0.00 | 1.00 | 0.14 | *0.00 | *0.01 | 1.00 | 0.81 | 0.72 | 0.34 | 1.00 | 0.06 | *0.00 | *0.00 |
Focal adhesion | (4510) | 1.00 | *0.00 | *0.00 | *0.00 | 1.00 | 1.00 | 1.00 | 0.28 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Long-term pote… | (4720) | 1.00 | *0.00 | *0.01 | *0.04 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.37 | 1.00 | 1.00 | 1.00 | 1.00 |
Regulation of a… | (4810) | *0.00 | *0.00 | *0.00 | *0.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Phosphatidylino… | (4070) | 1.00 | 0.11 | *0.00 | 0.52 |  |  |  |  | 1.00 | 1.00 | 0.54 | 1.00 | 1.00 | 1.00 | 0.21 | 1.00 |
Wnt signaling | (4310) | *0.00 | 1.00 | *0.00 | *0.03 | 1.00 | 1.00 | 0.92 | 1.00 | 1.00 | 1.00 | 1.00 | 0.91 | 1.00 | 1.00 | 1.00 | 1.00 |
Adherens junct… | (4520) | 1.00 | *0.00 | 0.13 | *0.00 |  |  |  |  | 0.95 | 0.31 | 0.96 | 0.38 | 1.00 | 1.00 | 0.48 | *0.01 |
Ubiquitin media… | (4120) | 1.00 | 1.00 | 1.00 | 0.13 |  |  |  |  | 1.00 | 1.00 | 1.00 | 0.92 | 1.00 | 1.00 | 1.00 | 0.17 |