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Table 1 Programs and their corresponding problem settings for epistasis detection in GWAS

From: Tools for efficient epistasis detection in genome-wide association study

Program

Trait

Genotype

Error Type

Sample Size

Supported Test

FastANOVA

quantitative

binary

FWER

less than a hundred

ANOVA test

COE

binary

binary

FWER

less than a hundred

convex test

TEAM

binary

any

FWER & FDR

hundreds to thousands

test based on contingency tables